RAS ACTIVATION ASSAY KIT

RAS ACTIVATION ASSAY KIT

Stock Code: 3586413
Manufacturer Part No: 17-218
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Components


Ras Assay Reagent (Raf-1 RBD, agarose) (Cat.# 14-278)Anti-Ras, clone RAS10 (Cat.# 05-516)100X GTPγS, 10mM (Cat.# 20-176)100X GDP, 100mM (Cat.# 20-177)Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)


Disclaimer


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


General description


Muscle RAS oncogene homolog (MRAS) plays a key role in cardiovascular diseases.The MRAS gene codes for a member of the ras superfamily of GTP-binding proteins. MRAS is found in all tissues, particularly in the cardiovascular system. It is involved in signal transduction, including cell growth and differentiation.


Legal Information


UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


Linkage


Replaces: SGT435


Packaging


Kit capacity: 30 assays


1 kit in Kit capacity: 30 assays


Quality


This kit precipitated Ras-GTP from HeLa cell lysates that had been loaded with GTPγS. The precipitated Ras-GTP was detected by western immunoblot using 1µg/ml anti-Ras, clone RAS10

Quality Level100
ManufacturerSIGMA-ALDRICH
Technique(s)activity assay: suitable

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