Analysis Note
To view the Certificate of Analysis for this product, please visit www.cytiva.com.
Application
Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles typical application uses include sample preparation, proteomics, nucleic acid isolation, and immunoassay applications.
Features and Benefits
Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles allow convenient covalent coupling of target molecules.•Carboxylic groups on the surface permit easy covalent coupling to biomolecules of interest using convenient carbodiimide chemistry.•Different levels of hydrophobicity/hydrophilicity available.•Available in Sera-Mag™ SpeedBeads and original Sera-Mag™ versions.•Excellent sensitivity and low nonspecific binding for greater accuracy.•Fast Magnetic Response Times and Stable Physical Integrity.•Unique cauliflower-like surface increases overall binding capacity.•Salt-tolerance and slow settling rate provides excellent colloidal stability in the absence of a magnetic field.•Uniform diameter provides high surface area and excellent lot-to-lot reproducibility.•Surfactant-free particles require no washing.•Stability in buffer systems and detergents allows versatility in reagent and sample preparation.•Fast reaction kinetics increases throughput and precision.
Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles allow convenient covalent coupling of target molecules.•Carboxylic groups on the surface permit easy covalent coupling to biomolecules of interest using convenient carbodiimide chemistry.•Different levels of hydrophobicity/hydrophilicity available.•Available in Sera-Mag™ SpeedBeads and original Sera-Mag™ versions.•Excellent sensitivity and low nonspecific binding for greater accuracy.•Fast Magnetic Response Times and Stable Physical Integrity
General description
Sera-Mag™ SpeedBeads and Sera-Mag™ Carboxylate-Modified Magnetic Particles combine a fast magnetic response time and high binding capacity with a large surface area, high sensitivity, stability, physical integrity, and fast reaction kinetics. Covalent coupling of biomolecules such as proteins and nucleic acids to carboxyl groups on the surface is easily accomplished using our standard coupling technology. The core of the particle is made by a free radical emulsion polymerization of styrene and acid monomer. One (Sera-Mag™) or two (Sera-Mag™ SpeedBeads) layers of magnetite are then coated onto this core, while the surface is modified to minimize non-specific binding of proteins.
Legal Information
Sera-Mag is a trademark of Cytiva
Storage and Stability
Unless otherwise stated, refrigerate (2-8 °C) product when not in use but do not freeze. Store upright and keep bottle tightly sealed. Mix product with gentle inversion by hand, roller or vortex mixer.