Con-A Sepharose 4B, Cytiva, 17-0440-03, pack of 5 mL

Stock Code: 2796174
Manufacturer Part No: GE17-0440-03

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Descriptions

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Application

Con A Sepharose^® is Concanavalin A coupled to Sepharose^® 4B by the cyanogen bromide method. Concanavalin A (Con A) is a tetrameric metalloProtein isolated from Canavalia ensiformis (jack bean). Con A binds molcules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. The binding sugar requires the presence of C-3, C-4 and C-5 hydroxyl groups for reaction with Con A. Con A coupled to Sepharose^® is routinely used for separation and purification of glycoProteins, polysaccharides and glycolipids

Features and Benefits

Concanavalin A (Con A) binds molecules that contain α-D-mannose, α-D-glucose, and sterically related residues with available C-3, C-4, or C-5 hydroxyl groups Group-specific adsorbent for molecules containing sugars. Highly suitable for isolation of cell surface glycoProteins from detergent-solubilized membranes Concanavalin A (Con A) binds molecules that contain α-D-mannose, α-D-glucose and sterically related residues with available C-3, C-4, or C-5 hydroxyl groups Highly suitable for isolation of cell surface glycoProteins from detergent-solubilized membranes Con A coupled to Sepharose^® 4B via cyanogen bromide activation

General description

Con A Sepharose^® 4B with immobilized Concanavalin A is an affinity chromatography media for capture of glycosylated biomolecules including glycoproteins and glycolipids. Stronger affinity for α-D-glucose than α-D-mannose.

Legal Information

Sepharose is a registered trademark of Cytiva