ROCHE Mitomycin C

ROCHE Mitomycin C

Stock Code: 2795359
Manufacturer Part No: 10107409001
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Application


Mitomycin C is used as an inhibitor for studies of cell-free protein biosynthesis. It also inhibits DNA synthesis. It has been used as a genotoxic agent for tumor cells.


Mitomycin C has been used: to cease mitosisin phosphate buffer saline (PBS)for inactivation and plating mouse embryonic fibroblasts (MEFs)as mutagen in mutagenicity assay


Biochem/physiol Actions


Mitomycin C (MMC) acts as a prototype for drugs with bioreductive alkylation. It is mainly found to be active under anaerobic conditions.MMC exhibits a vast clinical antitumor spectrum effectively in gastric, pancreatic and breast cancer.


General description


Mitomycin C is an antitumor antibiotic.


Other Notes


For life science research only. Not for use in diagnostic procedures.

InChI keyNWIBSHFKIJFRCO-WUDYKRTCSA-N
InChI1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
Formcrystalline powder
Assay98%

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