CUDC 101, A potent inhibitor of HDACs and receptor tyrosine kinases

CUDC 101, A potent inhibitor of HDACs and receptor tyrosine kinases

Stock Code: 2794871
Manufacturer Part No: EPS003-5MG
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General description


A potent multitargeted inhibitor of histone deacetylase (HDAC) and the receptor kinases epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), with IC50 values of 4.4, 2.4, and 15.7 nM, respectively.Displays potent antiproliferative and proapoptotic activities against cultured and implanted tumor cells that are sensitive or resistant to several approved single-targeted drugs.

Colourwhite
Quality Level100
Storage Temp.−20°C
SolubilityDMSO: soluble
Assay≥98% (HPLC)

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