Urea solution is primarily used for protein denaturation. It also increases solubility of hydrocarbons and reduce micelle formation. Urea solution at high concentration leads to the destabilization of amyloid ?16?22 oligomers.
Preparation Note
Warm the refrigerated 40% urea solution to room temperature. Aseptically add 5 mL to 95 mL of sterile molten Urea Agar Base (Christensen). Mix well and dispense in sterile tubes.