Protein Kinase G Ibeta human, >=95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 c

Protein Kinase G Ibeta human, >=95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf9 c

Stock Code: 3581049
Manufacturer Part No: P3738-5UG
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Application


Protein Kinase G is a serine/threonine-specific protein kinase that is activated by cGMP. Protein Kinase G I? is used to induce apoptosis and inhibit cell proliferation.


Biochem/physiol Actions


Protein Kinase G I? induces apoptosis in certain cell lines such as human breast cancer cell lines MCF-7 and MDA-MB-468. It inhibits cell proliferation and induces apoptosis in colon cancer cell lines.


Physical form


Solution in 20 mM Tris buffer, pH 7.4, 1 mM EDTA, 1 mM β-mercaptoethanol, 100 mM NaCl, 10 U/ml Trasylol, and 50% glycerol.


Unit Definition


One unit will phosphorylate 1 micromole of VASPtide(RRKVSKQE) substrate per minute in 10 mM HEPES, pH 7.4, 5 mM MgCl2, 1 mM DTE and 0.2 mM EDTA.

Quality Level200
ManufacturerSIGMA-ALDRICH
Formbuffered aqueous glycerol solution
Assay≥95% (SDS-PAGE)

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