Phosphodiesterase I from Crotalus adamanteus venom, Type VI, crude dried venom, >=0.01 unit/mg solid

Stock Code: 3581037
Manufacturer Part No: P3134-100MG
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Application


Phosphodiesterase I from Crotalus adamanteus venom has been used:for cleaving the 3?-5? internucleotide bonds in the linear chains of the RNA oligomersas a model for the hydrolysis of prodrugs in phosphodiesterase assayas a component in the nucleotide cleavage buffer


Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is used in phosphodiesterase activation assays to hydrolyze AMP. Product P3134 is from crude, dried Crotalus adamanteus venom.


Biochem/physiol Actions


Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formcrude dried venom

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