Flavin-Containing Monooxygenase-5, Microsomes human, recombinant, expressed in baculovirus infected

Flavin-Containing Monooxygenase-5, Microsomes human, recombinant, expressed in baculovirus infected

Stock Code: 3579446
Manufacturer Part No: F5178-1VL
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Application


FMO5 is the only FMO isoform expressed in both adult and fetal human liver.


Biochem/physiol Actions


FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.


Physical form


Solution in 100 mM potassium phosphate buffer, pH 7.4.


Unit Definition


methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

Quality Level200
ManufacturerSIGMA-ALDRICH
Formbuffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

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