Creatine Kinase MB Fraction from human heart, >=70% (SDS-PAGE), liquid

Stock Code: 3579112
Manufacturer Part No: C0984-100UG
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Application


Enzyme associated with coronary performance.


The MB isoenzyme of creatine kinase (MBCK) can be used as a diagnostic marker for acute myocardial infarction.


Biochem/physiol Actions


Creatine Kinase (CK) catalyzes the formation of creatinine from creatine phosphate. Elevated serum levels of CK-MB are prime indicators of myocardial cellular injury. It is regarded as a “gold standard” for myocardial infarction diagnosis. The levels of cardiac troponin I (cTnI) or cardiac troponin T also correlate to higher CK-MB) levels. CK-MB levels may also be elevated in chronic renal failure.


Components


Solution in 5?mM sodium succinate, 10 mM sodium chloride, 1?mM EDTA, 5?mM β-mercaptoethanol, 50% glycerol, pH 7.0.


General description


Creatine Kinase (CK) comprises M and B subunit and is a dimeric molecule. It is one among the isoenzymes of CK. The enzyme is majorly present in the myocardium.

Quality Level200
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formliquid
Assay≥70% (SDS-PAGE)

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