Acetylcholine chloride, pkg of 150 mg (per vial)

Acetylcholine chloride, pkg of 150 mg (per vial)

Stock Code: 3578104
Manufacturer Part No: A9101-10VL
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Application


For use as a substrate to determine acetylcholinesterase activity. Acetylcholine chloride has been used:for standard curve preparation in hestrin assayin Protein expression, radioactive ligand binding assay and electrophysiological studies of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBPs)as a supplement in extracellular solutions for treating the voltage clamped cells in electrophysiology studies


Biochem/physiol Actions


Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.


Acetyl choline (ACh) is an essential neurotransmitter in both central and peripheral nervous system. ACh binds to nicotinic acetylcholine receptors (nAChRs) and causes fast excitatory neurotransmission.


Reconstitution


Reconstituted solution is stable for 2 weeks when stored at 2-8?°C

Quality Level100
mp146-150 °C (lit.)
InChI keyJUGOREOARAHOCO-UHFFFAOYSA-M
InChI1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
SolubilityH2O: soluble
Formpowder or crystals
Assay≥99% (TLC)

There are no downloads for this product.