Tolfenamic acid, NSAID

Stock Code: 3577916
Manufacturer Part No: T0535-5G
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£107.11 (exc VAT) per 5G
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Application


Tolfenamic acid has been used in Arabidopsisbud assay for activity comparison with quinazolinedione derivatives (QADD) based compounds.


Biochem/physiol Actions


Tolfenamic acid is involved in the inhibition of prostaglandin synthesis. It also plays a role in apoptosis of head and neck cancer cells.


Non-steroidal anti-inflammatory agent. Interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor.


General description


Tolfenamic acid is a fenamate and is made up of a monocarboxylate diphenylamine nucleus.


Packaging


5 g in glass bottle

Quality Level200
InChI keyYEZNLOUZAIOMLT-UHFFFAOYSA-N
InChI1S/C14H12ClNO2/c1-9-11(15)6-4-8-12(9)16-13-7-3-2-5-10(13)14(17)18/h2-8,16H,1H3,(H,17,18)
ManufacturerSIGMA-ALDRICH
Solubilityethanol: 50 mg/mL, clear, greenish-yellow
Formpowder
Assay≥98% (TLC)

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