Human Amyloid # 42 High Sensitive ELISA

Stock Code: 3577541
Manufacturer Part No: EZHS42

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Descriptions

Application

Used to detect/quantify: Amyloid β42

This assay requires 50 µl of sample and is an overnight assay.

Research CategoryNeuroscience

This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.

Research Sub CategoryAlzheimer′s Disease

Disclaimer

For research use only. Not for use in diagnostic procedures.

General description

Amyloid beta peptides have been implicated in the etiology of Alzheimer's disease. Amyloid beta 40 is the most prominent peptide and Amyloid beta 42 is the neurotoxic form. The Amyloid beta 42/40-ratio (AB ratio) has been reported as a better indicator of the Alzheimer pathology. Millipore's High Sensitivity Human Amyloid β42 ELISA kit is used for the measurement of Amyloid β42 in cerebrospinal fluid, cell culture supernatants, primary neurons and plasma in a 96-well format.

Other Notes

Please contact Technical Service for linearity of dilution.

Specificity

The Amyloid β42 ELISA (HS) uses monoclonal anti-Aβ antibodies with high selectivity for human Aβ. The capture antibody recognizes the C-terminal end of Amyloid β1-42, which causes a high selectivity for Aβ42. The cross-reactivity of the used antibodies to other Amyloid peptides was tested by ELISA and BIACORE and shows no significant cross-reactivity to Aβ1-38, Aβ1-39, Aβ1-40, Aβ1-43 and Aβ1-44.

Storage and Stability

Components in the kit can be stored up to 2 weeks at 2-8°C