GLP-2 ELISA Kit (BULK PK) 10 plates

Stock Code: 3577510
Manufacturer Part No: EZGLP2-37BK
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Application


Used to detect/quantify: GLP-2


This assay requires 50 µl of rat or human samples and is performed at room temperature as a 4 hour assay. GLP-2 has also been detected in guinea pig, horse, porcine, and non-human primate samples.


Research CategoryMetabolism


Research Sub CategoryOsteoporosis


Disclaimer


For research use only. Not for use in diagnostic procedures.


General description


The glucagon-like peptides GLP-1 and GLP-2 are important gut hormones released from the small intestine upon nutrient ingestion. In circulation, GLP-2 is present in two molecular forms, GLP-2 (1-33) and GLP-2 (3-33). Similar to GLP-1, active form GLP-2 (1-33) is cleaved to inactive form GLP-2 (3-33) by protease DPPIV. GLP-2 has been shown to play important roles in the regulation of gastrointestinal functions (digestion, absorption, motility, epithelial growth, and blood flow) and bone resorption. Thus, GLP-2 or its analogs may have therapeutic potentials for the treatment of diseases such as Crohn's disease and osteoporosis.


Other Notes


Please contact Technical Service for linearity of dilution.


Specificity


Human GLP-2 1-33 100%
Human GLP-2 3-33 112%
Rat GLP-2 101%

Quality Level100
ManufacturerSIGMA-ALDRICH
Technique(s)ELISA: suitable

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