VALRUBICIN

VALRUBICIN

Stock Code: 3576425
Manufacturer Part No: SML2516-20MG
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Biochem/physiol Actions


Valrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. Valrubicin is converted intracytoplasmically into N-trifluoroacetyladriamycin, which interacts with topoisomerase II, stabilizing the complex between the enzyme and DNA and causing cell cycle arrest.

InChI keyZOCKGBMQLCSHFP-ZQUOIQDWSA-N
InChI1S/C34H36F3NO13/c1-4-5-9-21(40)49-13-20(39)33(47)11-16-24(19(12-33)51-22-10-17(27(41)14(2)50-22)38-32(46)34(35,36)37)31(45)26-25(29(16)43)28(42)15-7-6-8-18(48-
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
Formpowder or crystals

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