NEDAPLATIN

NEDAPLATIN

Stock Code: 3576424
Manufacturer Part No: SML2514-50MG
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Biochem/physiol Actions


Nedaplatin is a second-generation cisplatin analog with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. Nedplatin is less nephrotoxic and neurotoxic compared to both cisplatin and carboplatin.

InChI keyKLNFSAOEKUDMFA-UHFFFAOYSA-N
InChI1S/C2H4O3.2H2N.Pt/c3-1-2(4)5;;;/h3H,1H2,(H,4,5);2*1H2;/q;2*-1;+2
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
Formpowder

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