ANDRASTIN A

ANDRASTIN A

Stock Code: 3576242
Manufacturer Part No: SML2385-1MG
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Biochem/physiol Actions


Farnesyltransferase inhibitor with anticancer activity; mycotoxin


Andrastin A is a meroterpenoid protein farnesyltransferase inhibitor with anticancer activity. It has been shown to inhibit the farnesyltransferase activity of the oncogenic Ras proteins and inhibit the efflux of anticancer drugs from multidrug-resistant cancer cells.

Colourwhite to beige
InChI keyGRBXNADBNJGZRK-BCMOVVIDSA-N
InChI1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3/t16?,18?
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formpowder
Assay≥95% (HPLC)

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