IWP-O1

IWP-O1

Stock Code: 3575626
Manufacturer Part No: SML1962-5MG
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Biochem/physiol Actions


IWP-O1 is an inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase essential for secretion of Wnt proteins and involved in both embryonic development and tumor progression. IWP-O1 has good metabolic stability and is extremely potent, exhibiting an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling.

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C
SolubilityDMSO: 25 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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