NSC73306

Stock Code: 3575517
Manufacturer Part No: SML1897-5MG

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Descriptions

Biochem/physiol Actions

NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells. Irrespective of variations in cell line background, NSC73306 consistently demonstrated a Pgp-potentiated MDR-selective toxicity. It appears that NSC73306 is transported into the cell by copper transporter 1 (CTR1, SLC31A1). It is not P-gp inhibitor.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	, yellow to light brown
Quality Level	100
InChI key	HPXWWBMVIMFLLU-UHFFFAOYSA-N
InChI	1S/C16H12Cl2N4O2S/c1-24-10-4-2-9(3-5-10)19-16(25)22-21-14-11-6-8(17)7-12(18)13(11)20-15(14)23/h2-7H,1H3,(H2,19,22,25)(H,20,21,23)
Manufacturer	SIGMA-ALDRICH
Storage Temp.	2-8°C
Solubility	DMSO: 10 mg/mL, clear
Form	powder
Assay	≥98% (HPLC)