8-AMINOGUANOSINE

8-AMINOGUANOSINE

Stock Code: 3575457
Manufacturer Part No: SML1852-25MG
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£92.76 (exc VAT) per 25MG
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Biochem/physiol Actions


8-Aminoguanosine, a guanosine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic that increased sodium excretion by 26.2-fold and decrease potassium excretion by 69.1%. 8-Aminoguanosine increases glucose excretion by 12.2-fold. Also 8-Aminoguanosine suppressed deoxycorticosterone/salt-induced hypertension.


8-Aminoguanosineis known to stimulate diuresis, natriuresis, glucosuria and antikaliuresis. It is an analog of guanosine, that can block purine nucleoside phosphorylase, in vitro and in intact lymphoid cells. 8-aminoguanosine triphosphate can be used to block GTP (guanosine triphosphate) cyclohydrolase I from human liver andEscherichia coli.


Packaging


25 mg in glass bottle

Colourwhite to brown
Quality Level100
InChI keyFNXPTCITVCRFRK-UHFFFAOYSA-N
InChI1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 1 mg/mL, clear (warmed)
Formpowder
Assay≥98% (HPLC)

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