VOSAROXIN HYDROCHLORIDE

Stock Code: 3575428
Manufacturer Part No: SML1823-25MG

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Descriptions

Biochem/physiol Actions

Vosaroxin is an anti-cancer quinolone derivative that acts as a DNA intercalator and a topoisomerase II inhibitor, causing p53 independent tumor cell apoptosis. Vosaroxin stabilizes cleavage complexes formed by topoisomerase IIα and IIβ, which results in an accumulation of DNA double-strand breaks. Vosaroxin showed antineoplastic activity in multiple solid tumor and hematologic cancer cell lines and has been in clinical trials for AML.

Packaging

5, 25 mg in glass bottle