CYCLOTRAXIN-B TRIFLUOROACETATE SALT

CYCLOTRAXIN-B TRIFLUOROACETATE SALT

Stock Code: 3575360
Manufacturer Part No: SML1769-1MG
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£285.54 (exc VAT) per 1MG
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Biochem/physiol Actions


Cyclotraxin-B is a potent and selective Trk B (BDNF/NT-3) receptor inhibitor. Cyclotraxin-B prevents receptor activation by BDNF without interfering with BDNF binding. Cyclotraxin-B has an IC50 value ﹤ 1 nM. In rodent studies Cyclotraxin-B, sometimes fused with tat-protein for increased brain permeability, has been shown to have anxiolytic properties, prevent cold hypersensitivity induced by BDNF, and to reduce cocaine self-administration.


Packaging


1 mg in glass bottle

Colourcolorless
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formfilm
Assay≥95% (HPLC)

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