MSP-3

Stock Code: 3575175
Manufacturer Part No: SML1623-5MG
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Biochem/physiol Actions


MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.

Colourwhite to beige
Quality Level100
InChI keyHCUVEUVIUAJXRB-UHFFFAOYSA-N
InChI1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
ManufacturerSIGMA-ALDRICH
Storage Temp.room temp
Formoil
Assay≥98% (HPLC)

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