FERUTININ

FERUTININ

Stock Code: 3575151
Manufacturer Part No: SML1609-5MG
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Biochem/physiol Actions


Ferutinin can suppress tumor development without causing systemic toxicity in various tumor cells and animal cancer models. It possesses estrogenic properties and a protective role against uterine carcinoma. Ferutinin exhibits anti-cancer action in estrogen-dependent breast cancer cells.


Ferutinin is a strong agonist for estrogen receptor (ER)α and agonist/antagonist for Erβ with IC50 values of 33.1 nM for ERα and 180.5 nM for Erβ. It has been shown to have both ionophoretic and apoptotic properties. It increases calcium permeability in the lipid bilayer and has been shown to improve bone regeneration in a rat study. It caused significant regression in tumor size in a mouse colon cancer model.


General description


Ferutinin, a daucanephytoestrogen, is found in the Ferula genus. It is a natural terpenoid and a calcium ionophore.


Packaging


5 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyCYSHNJQMYORNJI-YUVXSKOASA-N
InChI1S/C22H30O4/c1-14(2)22(25)12-11-21(4)10-9-15(3)13-18(19(21)22)26-20(24)16-5-7-17(23)8-6-16/h5-9,14,18-19,23,25H,10-13H2,1-4H3/t18-,19+,21-,22+/m0/s1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

There are no downloads for this product.