GAP19 TRIFLUOROACETATE SALT

Stock Code: 3574897
Manufacturer Part No: SML1426-1MG
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£275.79 (exc VAT) per 1MG
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Application


Gap19 trifluoroacetate salt has been used to inhibit Ca2+/calmodulin (CaM) gating response of connexin 43 (Cx43) gap junctions.


Biochem/physiol Actions


Gap19, nonapeptide from the cytoplasmic loop of Connexin-43, is a selective blocker of connexin 43 (Cx43) hemichannel that does not block GJ or Cx40/Panx-1 channels in cardiomyocytes and astrocytes. Gap19 prevents Cx43 hemichannel opening and protect against myocardial ischemia/reperfusion injury.


Packaging


1 mg in glass bottle

Colourwhite to off-white
Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Formpowder
Assay≥95% (HPLC)

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