INGELOL-3-ANGELATE

INGELOL-3-ANGELATE

Stock Code: 3574745
Manufacturer Part No: SML1318-1MG
Order Now for 5 day delivery
£224.25 (exc VAT) per 1MG
Quantity: - +

Biochem/physiol Actions


Ingenol 3-Angelate is a diterpenoid ester isolated from Euphorbia peplus that induces rapid cell death with keratinocytes and some cancer cell lines. Ingenol 3-Angelate is a protein kinase C activator that displays potent antileukemic activity. Ingenol 3-Angelate (ingenol mebutate) is used for treatment of actinic keratosis.


Ingenol-3-angelate, is a phorbol ester-like compound or a diacylglycerol analog that is used in the treatment of several disorders like skin cancer. It is also known as PEP005. Ingenol-3-angelate stimulates the initiation of the enzyme by providing PKCs (protein kinase C) to cellular membranes.


Packaging


1 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyVDJHFHXMUKFKET-WDUFCVPESA-N
InChI1S/C25H34O6/c1-7-12(2)22(29)31-21-13(3)10-24-14(4)8-17-18(23(17,5)6)16(20(24)28)9-15(11-26)19(27)25(21,24)30/h7,9-10,14,16-19,21,26-27,30H,8,11H2,1-6H3/b12-7-/
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥95% (HPLC)

There are no downloads for this product.