Cyclic-Di-Gmp Sodium Salt

Cyclic-Di-Gmp Sodium Salt

Stock Code: 3574626
Manufacturer Part No: SML1228-1UMO
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Application


Cyclic-di-GMP sodium salt has been used as a quorum sensing molecule.


Biochem/physiol Actions


Cyclic-di-GMP is a naturally occurring small molecule that acts as a bacterial second messenger to regulate important signaling mechanisms in prokaryotes that control bacterial survival, adhesion, colonization, biofilm formation, and virulence factors production. During infections Cyclic-di-GMP is bound by host STING (stimulator of interferon genes) leading to expression of interferon genes, activating innate immune responses. c-di-GMP has been found in eukarotic systems acting not only in immune response, but as an inhibitor of the pacemaker I(f) current in the heart.


Preparation Note


Cyclic-di-GMP is soluble in water and aqueous buffers.

Colourwhite to beige
Quality Level100
ManufacturerSIGMA-ALDRICH
Further Infocontains 1µmol of powder (approx. 0.7mg)
Storage Temp.−20°C
Formpowder
Assay≥98% (HPLC)

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