PYZD-4409

PYZD-4409

Stock Code: 3574580
Manufacturer Part No: SML1188-5MG
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Biochem/physiol Actions


PYZD-4409 inhibts ATP-dependent activation of human ubiquitin activating enzyme E1 with an IC50 of 20 mM. PYZD-4409 induces cell death, and inhbits clonogenic growth of leukemia and myeloma cell lines, and inhibits leukemia xenograft tumor growth in mice.


Packaging


5, 25 mg in glass bottle

Colour, white to very dark brown
Quality Level100
InChI keyMSYMKEYWUWVZQY-UHFFFAOYSA-N
InChI1S/C14H7ClFN3O5/c15-10-5-7(1-3-11(10)16)18-14(21)9(13(20)17-18)6-8-2-4-12(24-8)19(22)23/h1-6H,(H,17,20)
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 10 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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