WZ4002

Stock Code: 3574556
Manufacturer Part No: SML1168-5MG

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Descriptions

Biochem/physiol Actions

WZ4002 is effective in the treatment of lung adenocarcinomas due to EGFR (epidermal growth factor receptor) mutations.

WZ4002 is an irreversible inhibitor of the gatekeeper EGFR-T790M mutation that binds to the active conformation of the EGFR kinase forming a covalent bond with Cys 797.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	white to beige
Quality Level	100
InChI key	ITTRLTNMFYIYPA-UHFFFAOYSA-N
InChI	1S/C25H27ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: 5 mg/mL, clear (warmed)
Form	powder
Assay	≥98% (HPLC)