ML303

Stock Code: 3574526
Manufacturer Part No: SML1145-25MG
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Biochem/physiol Actions


It belongs to the pyrazolopyridine family.


ML303 is a potent inhibitor (IC50 = 155 nM) of the influenza viral protien NS1. NS1 enhances virulence by inhibiting host cell immune responses, including the expression of IFN-b, and regulating synthesis, splicing and translation of viral RNA.


Packaging


5, 25 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyYBRHGNCGFMRGSV-UHFFFAOYSA-N
InChI1S/C21H16F3N3O2/c1-12-19-16(13-3-8-17(28)18(11-13)29-2)9-10-25-20(19)27(26-12)15-6-4-14(5-7-15)21(22,23)24/h3-11,28H,1-2H3
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: 20 mg/mL, clear
Formpowder
Assay≥98% (HPLC)

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