A-278637

Stock Code: 3574380
Manufacturer Part No: SML1033-25MG

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Descriptions

Biochem/physiol Actions

A-278637 is a selective opener of ATP-sensitive K (KATP) channels (EC₅₀ = 102 nM) that blocks contraction of bladder smooth muscle in both in vivo and in vitro assays. A-278637 is 15-fold more selective than nifedipine for bladder compared other smooth muscle KATP channels, and displays reduced effects on mean arterial pressure compared to other channel openers.

Packaging

5, 25 mg in glass bottle