BENZTROPINE MESYLATE

BENZTROPINE MESYLATE

Stock Code: 3574167
Manufacturer Part No: SML0847-500MG
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£61.15 (exc VAT) per 500MG
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Application


Benztropine mesylate has been used to study its target identification and mode of action against ebolavirus infection. It has also been used in pharmacological animal studies to evaluate its effect on SLC6A19 (solute carrier family 6 member 19; B0AT1).


Biochem/physiol Actions


Benztropine mesylate is a centrally acting muscarinic acetylcholine receptor antagonist and dopamine transporter (DAT) inhibitor (IC50 = 118 nM). Benztropine mesylate has been used to treat the symptoms of Parkinson′s disease and is currently in clincial trials for chronic back pain.


Benztropine mesylate serves as an inhibitor of breast cancer stem cells (BCSCs)in vitroandin vivo. It can help in improving the efficacy of chemotherapy in vitro. It is considered as an anti-cancer stem cell (CSC) drug, which can modify tumorigenic properties.


Features and Benefits


This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


This compound is featured on the Acetylcholine Receptors (Muscarinic) and Biogenic Amine Transporters pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


General description


Benztropine mesylate is an anti-histamine and dopamine re-uptake inhibitor.


Packaging


500 mg in glass bottle

Colourwhite to beige
Quality Level100
InChI keyCPFJLLXFNPCTDW-BWSPSPBFSA-N
InChI1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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