Staurosporine solution from Streptomyces sp., Ready Made Solution, 1 mM in DMSO (100 mug/214 muL), 0

Staurosporine solution from Streptomyces sp., Ready Made Solution, 1 mM in DMSO (100 mug/214 muL), 0

Stock Code: 3573919
Manufacturer Part No: S6942-200UL
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Application


Staurosporine solution from Streptomyces sp. was used to study the effect of PKC inhibition on signaling mediated by angiotensin II.3 It was used to induce cell death in Jurkat cells.4


Biochem/physiol Actions


Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.


Potent cell-permeable inhibitor of protein kinase C. Induces apoptosis in Jurkat cells.


General description


Chemical structure: indol derivative


Packaging


200 µL in glass bottle

Quality Level300
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Assay>98% (HPLC)

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