alpha-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, >=90% (S

alpha-Synuclein E46K human, recombinant, expressed in E. coli, N-terminal histidine tagged, >=90% (S

Stock Code: 3573909
Manufacturer Part No: S4447-500UG
Order Now for 7 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Biochem/physiol Actions


Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mutation is a 188G-A tran­sition resulting in a Glu46-to-Lys (E46K) substitution in the amino-terminal region of the protein.


Deposition of α-synuclein as fibrillary tangles is a hallmark of certain neurodegenerative diseases including Parkinson′s. Among the familial mutations of α-synuclein, E46K has the greatest potential to aggregate.

Quality Level200
ManufacturerSIGMA-ALDRICH
Compatibilityfor use with ABI StepOnePlus
Formlyophilized powder
Assay≥90% (SDS-PAGE)

There are no downloads for this product.