Pipamperone dihydrochloride, approx.99% (HPLC), powder

Stock Code: 3573531
Manufacturer Part No: P3246-100MG

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Descriptions

Application

Pipamperone dihydrochloride may be used: as an internal standard in liquid chromatography with coulometric detectionas an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channelas an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis

Biochem/physiol Actions

Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.

D₂ dopamine receptor antagonist; 5-HT₂ serotonin receptor antagonist; antipsychotic.

Features and Benefits

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

100 mg in poly bottle

Specifications

Colour	white
Quality Level	100
InChI key	BMXXSXQVMCXGJM-UHFFFAOYSA-N
InChI	1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H
Manufacturer	SIGMA-ALDRICH
Form	powder
Assay	~99% (HPLC)