NIDA-41020, >=97% (HPLC), solid

Stock Code: 3573507
Manufacturer Part No: N8162-50MG

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Descriptions

Biochem/physiol Actions

NIDA-41020 is a CB1 cannabinoid receptor antagonist. NIDA-41020 is structurally similar to Rimonabant, which is currently in clinical development. NIDA-41020 is less lipophilic; developed at NIDA as a potential radioligand for CB₁ receptors, K_i = 4.1 nM [in comparison AM 251, AM 281, SR 141716 (Rimonabant) have K_i of 0.6, 4.5 and 1.8 nM respectively].

Specifications

Colour	off-white
Quality Level	100
InChI key	KWDBQJRWPWTGPF-UHFFFAOYSA-N
InChI	1S/C23H24Cl2N4O2/c1-15-21(23(30)27-28-12-4-3-5-13-28)26-29(20-11-8-17(24)14-19(20)25)22(15)16-6-9-18(31-2)10-7-16/h6-11,14H,3-5,12-13H2,1-2H3,(H,27,30)
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: ~16 mg/mL, H2O: insoluble
Form	solid
Assay	≥97% (HPLC)