Mephetyl tetrazole, >=98% (HPLC), oil

Mephetyl tetrazole, >=98% (HPLC), oil

Stock Code: 3573480
Manufacturer Part No: M7945-5MG
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Biochem/physiol Actions


Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.


Features and Benefits


This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Packaging


5, 25 mg in glass bottle

Colourpale yellow
Quality Level100
InChI keyVREPWWBWXVLSEF-UHFFFAOYSA-N
InChI1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: >5 mg/mL
Formoil
Assay≥98% (HPLC)

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