Mephetyl tetrazole, >=98% (HPLC), oil

Stock Code: 3573480
Manufacturer Part No: M7945-5MG

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Descriptions

Biochem/physiol Actions

Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC₅₀ = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

Specifications

Colour	pale yellow
Quality Level	100
InChI key	VREPWWBWXVLSEF-UHFFFAOYSA-N
InChI	1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3
Manufacturer	SIGMA-ALDRICH
Solubility	DMSO: >5 mg/mL
Form	oil
Assay	≥98% (HPLC)