LOPAC,1280 - Small Scale,

Stock Code: 3573452
Manufacturer Part No: LO4100-1EA

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Descriptions

Application

LOPAC^® 1280 - Small Scale has been used: in sprouting assay to screen potential lymphangiogenic inhibitors and the signaling pathways involved in lymphangiogenesisfor identification of neuroactive compounds by measuring spontaneous activity within single zebrafish embryos by high-content screening assayfor high-throughput Screen for ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1; also known as CD39) and ecto-5?-nucleotidase (CD73) inhibitors

Features and Benefits

Includes the latest, drug-like molecules in the fields of Cell Signaling & Neuroscience: Apoptosis G Proteins & Cyclic Nucleotides Gene Regulation & Expression Ion Channels Lipid Signaling Multi-Drug Resistance Neurotransmission Phosphorylation

SDFile provided to construct a database containing: Structure Primary Name Secondary Name Pharmacological Activity Product Number Rack Position

General description

Compounds are arranged in 96-well format in 16 racks of 80, one compound per well (25 µl at 10 mM in DMSO in archival storage racks).

LOPAC^® 1280 is an extensively used library of pharmacologically active compounds. This library includes 1,280 marketed drugs, failed development candidates, and small molecules with well-characterized activities. LOPAC 1280 spans a broad molecular weight range, exhibits multiple mechanisms of action and interacts with a variety of biological receptors.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Other Notes

For sale inside of the U.S. only. Customers outside the US should refer to Product Code LO4200.