LFM-A13, >=98% (HPLC), powder

LFM-A13, >=98% (HPLC), powder

Stock Code: 3573447
Manufacturer Part No: L6920-5MG
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Biochem/physiol Actions


LFM-A13 is an inhibitor of the nonreceptor tyrosine kinase Bruton′s tyrosine kinase (Btk), a new molecular target for treatment of B-cell lymphoma and autoimmune disorders. LFMA13 inhibited recombinant BTK with an IC50 value of 2.5microM with 100-fold lower inhibitory activity against a number of other protein kinases including JAK1, JAK2, EGFR, IRK, IKK, and CDK1, 2 and 3, as well as several other related kinases


Features and Benefits


This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


Packaging


5, 25 mg in glass bottle

Colourwhite to tan
Quality Level100
InChI keyUVSVTDVJQAJIFG-VURMDHGXSA-N
InChI1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-
ManufacturerSIGMA-ALDRICH
SolubilityDMSO: ≥19 mg/mL
Formpowder
Assay≥98% (HPLC)

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