ICI 192605, >=98% (HPLC)

ICI 192605, >=98% (HPLC)

Stock Code: 3573404
Manufacturer Part No: I2536-25MG
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Biochem/physiol Actions


ICI 192605 is a potent thromboxane A2 receptor antagonist. It inhibits platelet aggregation and can reverse the effects of vasoconstrictors such as TXA2 or PGD2. ICI 192605 can reverse vasoconstriction induced by inhibition of NO production by L-NEMA, which leads to an increase in TXA2 release.


Features and Benefits


This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


Packaging


5, 25 mg in glass bottle

Colourwhite to tan
Quality Level100
InChI keyWHUIENZXNGAHQI-YGPRPMEGSA-N
InChI1S/C22H23ClO5/c23-18-11-6-4-9-16(18)22-27-14-15(8-2-1-3-13-20(25)26)21(28-22)17-10-5-7-12-19(17)24/h1-2,4-7,9-12,15,21-22,24H,3,8,13-14H2,(H,25,26)/b2-1-/t15-,
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥98% (HPLC)

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