Goserelin acetate, >=99% (HPLC), white powder

Stock Code: 3573382
Manufacturer Part No: G4919-5MG
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Amino Acid Sequence


Glp-His-Trp-Ser-Tyr-Ser(tBu)-Leu-Arg-Pro-azaGly-NH2


Biochem/physiol Actions


Goserelin acetate peptide results in significant inhibition of gonadotropin release and suppresses steroidogenesis in ovaries and testis. Thus, it leads to a reduction of testosterone to castration levels and estrogen to postmenopausal levels. Therefore, this peptide is used for reducing testosterone levels in patients with locally advanced prostate cancer.


Goserelin is a synthetic analog of LHRH (leutinizing hormone releasing hormone). Goserelin is a LHRH agonist It is used in prostate cancer and breast cancer therapies and also in the treatment of endometriosis.


General description


Goserelin acetate is a synthetic decapaptide, which is a potent analog of LHRH (luteinizing hormone releasing hormone).


Goserelin is used to guard ovary during breast-cancer adjuvant chemotherapy.

Colourwhite
Quality Level200
InChI keyIKDXDQDKCZPQSZ-JHYYTBFNSA-N
InChI1S/C59H84N18O14.C2H4O2/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-1
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥99% (HPLC)

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