EMETINE DIHYDROCHLORIDE HYDRATE

EMETINE DIHYDROCHLORIDE HYDRATE

Stock Code: 3573347
Manufacturer Part No: E2375-250MG
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Application


Emetine dihydrochloride has been used:as a protein synthesis inhibitor to study its effects on human papillomavirus type 8 E2 protein half-lifeto study its effects on the stress granules assemblyas a chain-elongation inhibitor in puromycin assay for protein synthesis


Biochem/physiol Actions


Emetine dihydrochloride is a member of the ipecac alkaloids family. It can mediate inhibition of protein and nucleic acid synthesis. It exhibits antiviral activity against dengue virus infection and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emetine dihydrochloride exhibits anti-proliferative effects against bladder cancer cells. It also possesses anti-protozoal activity.


Features and Benefits


This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


Packaging


1, 5 g in poly bottle

Quality Level100
mp240-250 °C (dec., dry matter) (lit.)
InChI keyIZTPMTAWOCEKKM-VXMYZLRESA-N
InChI1S/C29H40N2O4.2ClH.H2O/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24;;;/h13-16,18,21,24-25,30
ManufacturerSIGMA-ALDRICH
Storage Temp.2-8°C

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