Anti-CD349/Frizzled 9; clone W3C4

Stock Code: 3572078
Manufacturer Part No: MABD86

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Descriptions

Analysis Note

ControlWERI-RB-1 cells

Application

Research Sub CategoryPluripotent & Early DifferentiationDevelopmental Signaling

Anti-CD349/Frizzled 9 Antibody, clone W3C4 is an antibody against CD349/Frizzled 9 for use in Flow Cytometry.

Research CategoryStem Cell ResearchStem Cell Research

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 is an important factor for nervous system development and is critical for hippocampal development.

Immunogen

Whole WERI-RB-1 cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified by Ion-Exchange Chromatography

Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Format: Purified

Quality

Evaluated by Flow Cytometry on WERI-RB-1 cells Flow Cytometry Analysis: 4 µg/mL of this antibody detected CD349/Frizzled 9 on 1X10^5 WERI-RB-1 cells.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.