G 418 DISULFATE SALT SOLUTION

G 418 DISULFATE SALT SOLUTION

Stock Code: 3571742
Manufacturer Part No: G8168-50ML
Order Now for 21 day delivery
Click Add to Quote for price and delivery
Quantity: - +

Application


G418 disulfate is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 µg/mL or less while animal cells may require 300-500 µg/mL.


Biochem/physiol Actions


Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.


Caution


The product is stable for two years when stored at 2-8°C.


General description


Chemical structure: aminoglycoside

Colourcolorless
Quality Level200
Pack50ML
InChI keyUHEPSJJJMTWUCP-NKCAIAFTSA-N
InChI1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23
ManufacturerSIGMA-ALDRICH
Product LineBioReagent
Storage Temp.2-8°C
Impuritiesendotoxin, tested
SolubilityH2O: 50 mg/mL, clear
Formsolution

There are no downloads for this product.