Demeclocycline hydrochloride, >=90% (HPLC), powder

Demeclocycline hydrochloride, >=90% (HPLC), powder

Stock Code: 3571567
Manufacturer Part No: D6140-1G
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Biochem/physiol Actions


Used to study mechanisms of bacterial protein synthesis inhibition at the level of the 30S subunit and aminoacy-tRNA A-site binding.


Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.


Demeclocycline hydrochloride is a tetracycline antibiotic derived from a strain of Streptomyces aureofaciens. DMC protects neurons from glutamate induced toxicity by suppressing calpain I and II activities.


General description


Chemical structure: tetracycline

Quality Level200
Pack1G
InChI keyGVSJQNRGSCOSNJ-KBHRXELFSA-N
InChI1S/C21H21ClN2O8.ClH/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31;/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3
ManufacturerSIGMA-ALDRICH
Formpowder or crystals
Assay≥92% (HPLC)

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