Analysis Note
ControlSkin tissue, normal breast epithelium, melanocytes, mast cells and glial cells
Application
Research CategoryStem Cell Research
Flow Cytometry: 0.2 µg per 10e6 cells
Immunoprecipitation
Immunohistochemistry (Frozen)
Western blot
Blocking Ligand Binding
Optimal working dilutions must be determined by the end user.
Detect CD117 using this Anti-CD117 Antibody, clone ACK2 validated for use in FC, IH, IP, FUNC & WB.
Research Sub CategoryHematopoietic Stem CellsMesenchymal Stem Cells
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
This 145 kDa molecule is a member of the tyrosine kinase receptor family and is expressed by a majority of hematopoietic progenitor cells. The interaction of the mouse c-kit receptor and steel factor promotes proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells, and plays a role in signaling and activation of these cells.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Linkage
Replaces: CBL1360P
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Protein A purified
The monoclonal is presented in phosphate buffered saline containing 10mM sodium azide.
Format: Purified
Specificity
Specifically recognizes mouse CD117, known as c-kit receptor, stem cell factor receptor and steel factor receptor.
Storage and Stability
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Target description
145 kDa