Azaserine, Hybri-Max, gamma-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

Azaserine, Hybri-Max, gamma-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma

Stock Code: 3571289
Manufacturer Part No: A1164-.5MG
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Application


For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.


Biochem/physiol Actions


Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.


General description


Chemical structure: amino acid derivatives


Legal Information


Hybri-Max is a trademark of Sigma-Aldrich Co. LLC


Reconstitution


Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 µM azaserine.

InChI keyMZZGOOYMKKIOOX-VKHMYHEASA-N
InChI1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1
ManufacturerSIGMA-ALDRICH
Product LineBioXtra
Impuritiesendotoxin, tested
Formlyophilized powder

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