Galectin-1; Human; Recombinant; E. coli

Stock Code: 3571246
Manufacturer Part No: 345831-50UG
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General description


Recombinant human galectin-1 expressed in and purified from E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.


Recombinant, human galectin-1 expressed in E. coli. Galectins are a family of evolutionarily conserved animal lectins with affinity for β-galactosides that have homologous carbohydrate recognition domains (CRDs). Galectin-1 can induce apoptosis of activated T cells and leukemic T cell lines. It also binds to CD45 and inhibits its protein phosphatase activity.


Legal Information


CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Other Notes


Rabinovich, A., et al. 2002. Trends Immunol.23, 313.Rabinovich, A., et al. 2002. J. Leukoc. Biol.71, 741.Hughes, R.C., et al. 2001. Biochimie.83, 667.


Packaging


50 µg in Plastic ampoule


Physical form


Lyophilized from sterile-filtered 20 mM Tris-HCl, pH 7.5.


Preparation Note


Further dilute into aqueous buffers as needed.


Reconstitution


Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Diluted working solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.


Warning


Toxicity: Standard Handling (A)

Quality Level100
ManufacturerSIGMA-ALDRICH
Storage Temp.−20°C
Solubilitywater: 0.1-1 mg/mL
Formsolid
Assay≥98% (SDS-PAGE)

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