The Corning® Elplasia® 12K flask enables researchers to generate a high density of spheroids in a scaffold-free model. The Elplasia® 12K Flask contains 152 microcavities per cm2, in a vessel footprint similar to that of a T-75 flask. Gravity, in conjunction with the Corning® Ultra-Low Attachment (ULA) surface, and a rounded microcavity geometry enable formation of approximately 12,000 spheroids of similar shape and size. The ULA surface, a proprietary, animal-free, covalently bonded hydrogel, promotes the formation and easy harvesting of spheroids.
Corning ULA surface
Optically clear, gas permeable polystyrene film with low autofluorescence
Liquid diverter feature to minimise impact of liquid flow during medium exchange steps and flask handling
80cm2 surface area with 152 microcavities per cm2 generate approximately 12,000 spheroids of uniform size and shape per flask
Round well-bottom geometry
Microcavity geometry dimensions: 850 x 650µm (top diameter x depth), with working spheroid growth dimensions of 500 x 600µm (diameter x depth)
25 to 50mL working volume