[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate, >=97% (HPLC)

[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate, >=97% (HPLC)

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Amino Acid Sequence


Mpa-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 [Disulfide Bridge: 1-6]


Application


[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate has been used:in induction of antidiuresisas agonist of V2-receptor (V2R)for Von Willebrand factor (VWF) secretion in bleeding diathesis


[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate was used to study the impact of vasopressin on pendrin abundance. E3 ubiquitin (Ub)-protein ligases (E3s) was administered in rat kidney and the changes in protein abundance of the selected E3s in response to [deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate was examined.


Biochem/physiol Actions


[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate also known as DDAVP, Desmopressin is a selective and potent vasopressor agent that stabilizes the cardiocirculatory function in normal human as well as in patients suffering from catecholamine-resistant vasodilatory shock. It also stimulate three acid-base transporters and hence increases the capability of the cell to regulate pH.


Preparation Note


[deamino-Cys1, D-Arg8]-Vasopressin acetate salt hydrate dissolves in water at 20 mg/ml to yield a clear, colorless solution.

Quality Level200
InChI keyKWCKGAOCVGPZIC-VCCVNBJCSA-N
InChI1S/C46H64N14O12S2.C2H4O2.H2O/c47-35(62)15-14-29-40(67)58-32(22-36(48)63)43(70)59-33(45(72)60-18-5-9-34(60)44(71)56-28(8-4-17-52-46(50)51)39(66)53-23-37(49)64)2
ManufacturerSIGMA-ALDRICH
Formpowder
Assay≥95% (HPLC)

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